What is Optune Gio
Quick facts about Optune Gio
Long-term data
5-year
survival results in newly diagnosed GBM1
Experience
>25,000
patients with GBM started Optune Gio2
Availability
1,600+
certified medical centers prescribing Optune Gio for GBM3
What is Optune Gio?
Optune Gio is a wearable treatment delivery system that can provide continuous anti-cancer therapy*
- Small and lightweight, at just 2.7 pounds4
- Designed for convenience, carrying comfort, and usability
- Wearable and portable for use during most normal daily activities
How Optune Gio works
Optune Gio leverages biophysical principles to disrupt tumor viability
- Watch how Tumor Treating Fields can disrupt cancer cell division. This video shows the mechanism of action of TTFields
Optune Gio can provide consistent, continuous anti-cancer treatment.1,*
Optune Gio uses alternating electric fields to target GBM cells.
*Continuous treatment requires patient to be wearing the powered device.
How Optune Gio is used
Transducer arrays are applied to the shaved scalp and must be changed at least 2 times per week (every 4 days, at most)5
- Arrays should always have good scalp contact
- Avoid activities that may result in the device or transducer arrays becoming wet. Getting the device wet may cause it damage2
Recommended usage goal for Optune is 18+ hours/day, which gives patients flexibility to decide which times of day are best for use2
Patients can benefit most from wearing Optune Gio for the recommended time6
- In the phase 3 pivotal trial, 75% of patients used Optune Gio 18 or more hours a day during the first 3 months of treatment
- 50% daily use was the threshold for significant survival benefit over TMZ alone
- 86% of patients received a survival benefit from Optune Gio, because they used it more than half the time (n=388/450)
Simple steps to start patients on Optune Gio
Novocure® has identified a 4-step process that may help your patients with GBM start Optune Gio and achieve their treatment goals.
- Discuss treatment plan with multidisciplinary team, patient, and caregiver
- Submit prescription order form and supporting documentation
- Follow-up 2 weeks post Optune Gio initiation to review integration and skin care
- Manage each patient via monthly follow-ups and review of the Optune Gio Usage Report
See the Optune Gio system in detail
References: 1. Optune Gio. Instructions For Use. Novocure; 2023. 2. Novocure Data on File US-DOF-0036. 3. Novocure Data on File OPT-115.3. 4. Kinzel A, Ambrogi M, Varshaver M, Kirson ED. Tumor treating fields for glioblastoma treatment: patient satisfaction and compliance with the second-generation Optune® system. Clin Med Insights Oncol. 2019;13:1179554918825449. doi:10.1177/1179554918825449 5. Optune. Patient Information and Operation Manual. Novocure; 2023. 6. Toms SA, Kim CY, Nicholas G, Ram Z. Increased compliance with tumor treating fields therapy is prognostic for improved survival in the treatment of glioblastoma: a subgroup analysis of the EF-14 phase III trial. J Neurooncol. 2019;141(2):467-473.